Malaria

MALARIA The disease dates back to ancient times and the Egyptian word ‘Aat’inscribed at the temple of Dendrah is supposed to indicate the annual recurrence of malaria. Periodic fevers were also noted by Hippocrates (460–377 BC), who classified them into quotidian, tertian, subtertian and quartan depending on their periodicity. Malarial epidemics plagued ancient Rome and the illness was familiar to Galen ((AD 130–201) and Aulus Cornelius Celsus (25 BC–AD 50). The introduction of cinchona in 1630 by Spanish physician Juan del Vego helped to differentiate malaria from other fevers, although nothing was known of the etiology.  Italian physician, Francesco Torti (1658–1741) introduced cinchona into Italy and coined the term ‘mal aria’ (bad air) for it in 1712. Johann Friedrich Meckel (1781–1833) noticed certain pigment in the cells of the spleen and blood in malaria, and this was confirmed by Rudolph Virchow (1821–1902). Their significance was not recognized until Alphonse Laveran(1845–1922), professor of pathological anatomy at the University of Rome, recognized in 1880 that they represented malarial parasites. Ettore Marchiafava (1847–1935) observed them in 1885 in red blood cells as hemocytozoa, described their life cycle, and a gave the first description of Plasmodium. Natives of some countries noticed the relationship of malaria to mosquito bites but this was not scientifically pursued until 1894 when Sir Patrick Manson (1844–1922) proposed the extracorporeal life cycle for the malarial parasite in the mosquito. His suggestion was followed up by Sir Ronald Ross(1857–1932) who demonstrated the presence of the parasite in the Anopheles mosquito in 1897. See cinchona bark, antimalarials.



Stamps on Malaria
Stamps on Malaria
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Algeria, History of Medicine, Malaria, François Clément Maillot, 40 f, 1952, used
Algeria, History of Medicine, Malaria, François Clément Maillot, 40 f, 1952, used
£5.00
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A Text Book of Pathology, MacCallum, Willia. George, Johns Hopkins  University, W B Saunders, Second Edition,1922
A Text Book of Pathology, MacCallum, Willia. George, Johns Hopkins University, W B Saunders, Second Edition,1922
£198.00
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Therapeutice Specialis Ad Febres Periodicas, Torti, Francisco, 1756, rare
Therapeutice Specialis Ad Febres Periodicas, Torti, Francisco, 1756, rare
£295.00
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Malaria and the Parasites of Malarial Fevers, Bignami, Marchiafava, New Sydenham Society 1894
Malaria and the Parasites of Malarial Fevers, Bignami, Marchiafava, New Sydenham Society 1894
£395.00
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